How Rosacea Differs From Acne With other some informations ( courtecy;- webMD )



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How Rosacea Differs From Acne

UPDATED 25 AUGUST 2015
What's happening to my skin?
I have depigmented skin patches all over my body, what could it be? An expert answers.
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We all have embarrassing questions that we’re too afraid to ask. Have no fear. In this weekly series Dr Rakesh Newaj tackles vitiligo.
Vitiligo is a common skin disease that affects the skin and mucous membranes (lips, genitals).  Some studies have shown that up to 2% of the population can be affected from this disease.  Vitiligo is characterised by depigmented patches all over the body and has an average age of onset of 20 years. It can however present at any age and in most cases is progressive.
The reason for its appearance is very complex and based mainly on theories. In brief, an insult to the colour producing cells of the skin (melanocytes), leads to their destruction and thus appearance of depigmented patches on the skin. There are several reasons put forward and the most common ones are listed in the table below:
Autoimmune
Antibodies produced by the body, cause destruction of the melanocytes quite similar to other autoimmune diseases, e.g. thyroid disease.
Melanocyte
The colour producing cells have a structural defect which leads to their early death, hence the patches
Free radicals
Oxidative stress from the accumulation of free radicals can lead to the destruction of the melanocytes
Nerves
The nerve fibres in the skin may be sending abnormal signals that cause destruction of the pigment producing cells
Vitiligo most commonly affects the hands, forearm and face. The mucous membranes including the lips, genitals and gingiva can also be involved. In some areas the hairs become grey, which points to a poor prognosis.
There are different types of Vitiligo based on the different shades of discoloration. However an easier working classification remains the localised type, generalised or universal disease.
1.     The localised type is usually a single patch covering a small area of the skin. It can be distributed along the area supplied by a particular nerve. This type of Vitiligo tends to stay stable and can be treated by surgical options.
2.     Generalised Vitiligo is much more common. It affects various areas of the body and commonly involves the fingers, lips, face and eyelids.  Rarely, this variety is associated with autoimmune disease like pernicious anaemia, diabetes and thyroid disease.
3.     Universal Vitiligo affects most of the body surface area. In these cases, patients should consider bleaching the rest of the pigments to have a uniform body colour. The famous singer, Michael Jackson, suffered from this variety.
Treatment
The latest international guidelines still advocates the early treatment with potent corticosteroids as the first choice.  The best success rate is achieved when it is combined with narrowband UVB sessions and results can be expected within three months.  Areas around the eyes can be treated with tacrolimus, due to its better safety profile.  Other topical treatments that are commonly used as alternatives are calcineurin inhibitors  and Khellin creams. Calcineurin inhibitors give good results when combined with NUVB. However its use is limited due to costs and can be only on small body surface. Khellin cream is also effective and can be used in combination with corticosteroids and NUVB for maximum benefit.
The most frequently used light therapies are narrowband UVB (NUVB) and excimer laser. The NUVB is very safe and can be administered to the whole body.  It is very affordable, safe and gives good result.  Patients can be administered 250-350 sessions with little side-effects. In my clinic, a combination of NUVB, corticosteroids and Khellin cream achieves the best results for my patients. As for the excimer laser, it can treat only small surfaces and can be very costly. It is useful around the eyes.
Surgical procedures are gaining popularity in the treatment of localised and stable disease.  Again most of them are combined with light therapy to stimulate the proliferation of the melanocyte.
Some of the procedures:
1.     Punch grafting is the transfer if small punches of normal skin to a depigmented area. Approximately 30% of the depigmented area is grafted and then NUVB is used to stimulate the melanocytes. It can be performed on small surface areas.
2.     Suction blister grafting is a technique, whereby only the superficial layer of normal skin is separated by a producing a blister. This skin is then grafted onto the abnormal area.
3.     Needling is a procedure where small needles are used at the edges of depigmented patches to create bruises. These bruises push the normal melanocytes into the affected areas. Several sessions are needed and light therapy is used in between to stimulate the proliferation of the cells.
4.     Smashed skin grafting is where superficial skin from a donor site is crushed into small pieces and grafted onto the Vitiligo patch. Good results can be obtained if the technique is well mastered.
5.     Autologous melanocyte grafting is performed in specialised centres only.  The colour producing cells are harvested, treated and cultured.  This is injected into the depigmented region and the process can be repeated a few times. It is very costly and advanced equipment and good laboratory technical staff is needed.
In some cases of progressive disease, the use of oral steroids can stop the progression of  the disease. It is used in very low doses  for a few months. However, it only stops the disease from getting worse and does not help in the repigmentation process of already affected areas.  At times, stable patches can be concealed with cosmetic camouflage and tattooing. The tattooing can achieve a near normal skin colour. However in cases of universal disease, the only option remains the  bleaching the rest of the skin to achieve uniformity.
The psychological impact of this disease can be immense and patients can become withdrawn and depressed.  Thus early treatment with a dermatologist with some psychological support can suppress the disease and help the person to lead a normal life.
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5 Ways Your Skin Is Telling You Something’s Wrong

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ATSUSHI YAMADA VIA GETTY IMAGES
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By Bahar Gholipour, Staff Writer 
Published: 07/21/2014 10:43 AM EDT on LiveScience
The largest organ in the body, the skin, is sometimes said to be a window into a person’s general well-being, because it can carry clues about the health of other organs. Changes in the skin, ranging from discoloration to new growth, may sometimes be early signs of more serious underlying health problems, dermatologists say.
“I think of us as medical detectives,” said Dr. Doris Day, a dermatologist at Lenox Hill Hospital in New York City. “I’m always looking for that clue — when did this change happen, why it’s here, what are the other symptoms … Those clues will help me find what’s going on inside, both in the mind and the body.”
A handful of skin changes have been commonly associated with internal diseases. When people spot these signs, they might need to see their doctor, Day said. [7 Weirdest Medical Conditions]
“A few weeks is not uncommon to have something come and go, but if it persists beyond that, I would say see your doctor — especially if it gets worse during that time,” Day said.
Rashes and patches on the skin
In general, a rash that does not respond to treatment, and is accompanied by other symptoms — such as fever, joint pain and muscle aches — could be a sign of an internal problem or infection. A rash may also occur due to an allergy or signal a reaction to a medicine, according to the American Academy of Dermatology (AAD).
A velvety rash on the back of the neck or around the arms, usually with a color slightly darker than the person’s normal skin tone, is a sign that the patient may have an increased risk for developing type 2 diabetes, Day said. “When I see that, I warn the patient to get their blood sugar checked, and watch their diet.”
Less commonly, the velvety rash — called acanthosis nigricans — could be a warning sign of cancer in an internal organ, such as the stomach or liver, according to Mayo Clinic.
A purple rash on the lower legs that does not respond to topical medication can be a sign of hepatitis C infection, Day said.
Bronzing of the skin and other discolorations
In people with diabetes, a bronzing of the skin can be a sign of a problem with iron metabolism, Day said. A yellowing of the skin, on the other hand, may signal liver failure, and may occur along with the yellowing of the whites of the eyes, Day said.
A darkening of the skin — mostly visible in scars and skin folds, as well as on joints, such as elbows and knees — could be a sign of hormonal disease, such as Addison’s disease, which affects the adrenal glands, according to the AAD.
New growths
People who see new growths on the skin should always have them looked at by a doctor, as they could be skin cancer, and are sometimes also a sign of internal disease or a genetic syndrome, according to the AAD.
For example, in a condition called eruptive exanthemas, yellow bumps on the arms, legs or rear could be a result of high triglyceride levels, signaling uncontrolled diabetes, according to the AAD.
The distribution pattern of acne also can provide clues about the underlying problem. In women, acne that appears mainly along the lower face or jaw line can be a sign of polycystic ovarian syndrome, Day said. The condition often causes other symptoms, such as weight changes, thinning hair and increased hair growth on the face, she said.
Nail changes
Changes in the color or shape of nails can often be a sign of deficiency or organ system issues, Day said.
For example, nail changes that look like fungal infection may actually be a result of psoriasis in the nails, even though the condition typically affects the skin. People who also have joint pain could have a form of arthritis called psoriatic arthritis, Day said.
In addition, liver problems and kidney problems can sometimes cause changes in the color of the nails, Day said.
Changes in skin’s hardness and dryness
High blood pressure and kidney problems sometimes result in a thickening of the skin on the shin, Day said. Moreover, very dry, itchy skin could be a sign of hormonal problems, such as an underactive thyroid, she said.
“If you are over 30 or 40, and you’ve never had eczema as a kid — and all of a sudden, your skin is dry and you seem to be getting eczema — that could be sign of a hormonal issue like low thyroid” function, Day said.
People with an autoimmune disease called systemic sclerosis may experience a swelling and hardening of the skin. In more severe cases, this could result in the hardening of internal organs, such as the lungs or heart, according to the AAD.
On the other hand, very loose and silky skin is a symptom of a rare connective tissue disease, called acquired cutis laxa, which could signal blood cancers such as lymphoma or multiple myeloma, and could progress to affect internal organs, according to the AAD.
Email Bahar Gholipour or follow her @alterwired. Follow LiveScience @livescienceFacebook & Google+. Originally published on Live Science.
Copyright 2014 LiveScience, a TechMediaNetwork company. 





<p>Smooth Skin</p>
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VICTORIA MOORHOUSE 
May 16, 2017 @ 8:00 pm
I’ve always considered my face the perfect product guinea pig. I’ve been fortunate enough to never suffer from severe sensitivities or acne, so trying out a new product or treatment never phased me. Those sheets you fill out before a facial explaining your concerns or past diagnoses? It’s a long list of N/A for me. Well, until four months ago.
In a beauty editor’s worst nightmare scenario, I came in contact with an ingredient in a mask that, low and behold to my knowledge, did not agree with my skin. I washed off the mask to find my skin bright red, tight, and stinging, and kind of like I had sat outside in the sun for five hours without SPF. I splashed my face with water, applied a cooling mask (which immediately stung), and put an ice pack to my face. After a few hours, my skin returned to a pink state, and I shrugged thinking it was just a bad reaction and that was that... But then the side effects continued. Over the next few weeks, my normal go-to products stung or burned, I was breaking out more, and I was blotchy. I started treating my skin with more anti-acne products, thinking I was dealing with a bout of blemishes. Finally, after a few weeks of trail and error, an itchy, pimply rash on my forehead that would not go away sent me to the dermatologist's office. Enough was enough. 
I explained everything to my dermatologist, Dr. Patricia Wexler, as it happened. The reason my skin was freaking out? I had completely compromised my skin barrier.
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She told me that the skin barrier holds high levels of ceramides that protect the immunologic and homeostatis health of the skin, which keeps out bacteria, allergens, and maintains moisture. "In your case, inflammation and an immune response caused this barrier impairment and the loss of moisture from your skin," she said.
The side effects of this, she explained, tend to be inflamed, dry skin, which is exactly what I was dealing with. To make matters worse, my impairment triggered an eczema response, to which I figured was acne and started treating as so. The result of that bad idea? Even more irritated skin because I was sucking whatever moisture I had left out of my face.
Now, allergic reactions aren't the only cause of barrier impairment. Atopic dermatitis (eczema), according to Dr. Wexler, is actually the suspect. "Other causes of barrier impairment include excessive washing with soap, dust mite proteases, infections such as staph aureus, and topical allergens," she noted.
The fix was completely transforming my beauty routine, cutting most of my serums, oils, and favorite cleansers out and swapping them for mild (read: less likely to irritate and with little actives) formulas that were heavy in moisture to build up my barrier once again. I also had to cut the acne products because they weren't doing anything for the rash of eczema on my forehead.
Dr. Wexler recommended a gentle micellar water, like Simple's Micellar Cleansing Water ($9; target.com), Eucerin Eczema Relief Creme ($8; walgreens.com), a prescription for my rash on my forehead, Elta MD Clear SPF Broadspectrum 46 ($33; dermstore.com), and SkinMedica HA5 Rejuvenating Hydrator ($178; dermstore.com). And that, my friends, was all I was told to use. I was also instructed to pat all my products on my face, instead of rubbing which could trigger a histamine response. 
Over six weeks, the redness faded, the rash on my forehead completely cleared up, and my skin felt and looked like my moisture levels were rising. The stinging subsided, and I started to feel more confident not wearing foundation or concealer on the weekends because my tone was getting back to normal. 
So am I cured? Maybe, but maybe not. According to Dr. Wexler, patients that have barrier issues could have a genetic predisposition and should be extremely careful so another episode doesn't arise. However, if it's due to an allergen, which seems likely in my face, recurrences aren't expected.  
When skin returns to total normality, Dr. Wexler said patients can slowly add back in favorite products.
My suggestion? If you're dealing with a bad reaction to a product, don't diagnose yourself and go see a dermatologist as soon as you can. If you already know you have barrier impairment, consider following some of Dr. Wexler's tips or exactly what your skincare pro tells you to do. 
While I'm so excited to give my anti-aging serum the limelight once again, I will definitely be taking it one tub of cream at a time






A middle-aged woman suffers from rosacea.

Rosacea facts

  • Rosacea is a common, chronic, incurable, adult acne-like skin condition that is easily controllable and medically manageable.
  • Rosacea commonly affects the central third of the face, especially the nose, and its intensity varies over time.
  • Rosacea symptoms and signs include
  • Rosacea may be mistaken for rosy cheeks, sunburn, or quite often, acne.
  • Rosacea triggers include alcohol, hot or spicy foods, emotional stresssmoking, and heat.
  • Rosacea can be a very bothersome and embarrassing condition.
  • Untreated rosacea tends to worsen over time.
  • Prompt recognition and proper treatment permit people with rosacea to enjoy life.


Adult Skin Diseases


Photodynamic Therapy & Rosacea

In dermatology, PDT with the photosensitizer Levulan Kerastick (20% delta-aminolevulinic acid HCl) is used for the treatment of very early, thin skin cancers called actinic keratoses (AK). The initial approval was specifically for the treatment of actinic keratosis of the face and scalp with a combination of an application of the photosensitizer followed by a timed exposure to a special blue light source. PDT is also used for acne, rosacea, skin cancer, sun damage, cosmetic skin improvement, oily skin, enlarged sebaceous glands, wrinkles, rejuvenation (anti-aging), warts, hidradenitis suppurativa, psoriasis, and many other skin conditions.
An infographic displays the signs and symptoms of rosacea.

What is rosacea? Is rosacea contagious? What does rosacea look like?

Rosacea (ro-zay-sha) is a common, acne-like benign inflammatory skin disease of adults, with a worldwide distribution. Rosacea is estimated to affect at least 16 million people in the United States alone and approximately 45 million worldwide. Most people with rosacea are Caucasian and have fair skin. The main symptoms and signs of rosacea include red or pink facial skin, small dilated blood vessels, small red bumps sometimes containing pus, cysts, and pink or irritated eyes. Many people who have rosacea may just assume they have very sensitive skin that blushes or flushes easily.
Rosacea is considered an incurable auto-inflammatory skin condition which waxes and wanes. As opposed to traditional or teenage acne, most adult patients do not "outgrow" rosacea. Rosacea characteristically involves the central region of the face, mainly the forehead, cheeks, chin, and the lower half of the nose. It is most commonly seen in people with light skin and particularly in those of English, Irish, and Scottish backgrounds. Some famous people with rosacea include the former U.S. President Bill Clinton and W.C. Fields. Rosacea is not directly caused by alcohol intake, but it can be aggravated by it. Rosacea is not considered contagious or infectious.
The redness in rosacea, often aggravated by flushing, may cause small blood vessels in the face to enlarge (dilate) permanently and become more visible through the skin, appearing like tiny red lines (called telangiectasias). Continual or repeated episodes of flushing and blushing may promote inflammation, causing small red bumps, or papules, that often resemble teenage acne. Rosacea is also referred to as acne rosacea. One of the most unpleasant aspects of rosacea is the overgrowth of dermal tissues producing a "phymatous" change in the skin. This appears as a thickening and permanent swelling of the facial tissues. A bulbous nose called rhinophyma is an example of this change.
A teen boy with acne.

Is rosacea like acne?

Rosacea, although distinct from acne, does have some similarities. It is occasionally referred to as "adult acne." Unlike common acne, rosacea occurs most often in adults (30-50 years of age). Unlike acne vulgaris, rosacea is devoid of blackheads and characteristically does not resolve after puberty. Rosacea strikes both sexes and potentially all ages. It tends to be more frequent in women but more severe in men. It is very uncommon in children, and it is less frequent in people with dark skin.


An older man has symptoms and signs of rosacea across his nose and cheeks.

What are causes and risk factors of rosacea?

The exact cause of rosacea is still unknown. The basic process seems to involve dilation of the small blood vessels of the face. Currently, it is believed that rosacea patients have a genetically mediated reduction in the ability to dampen facial inflammation that is incited by environmental factors such as sunburn, demodicosis (Demodex folliculorum in the hair follicles), flushing, and certain medications. Rosacea tends to affect the "blush" areas of the face and is more common in people who flush easily. Additionally, a variety of triggers are known to cause rosacea to flare. Emotional factors (stress, fear, anxiety, embarrassment, etc.) may trigger blushing and aggravate rosacea. A flare-up can be caused by changes in the weather, like strong winds, or a change in the humidity. Sun exposure and sun-damaged skin is associated with rosacea. Exercise, alcohol consumption, smoking, emotional upsets, and spicy food are other well-known triggers that may aggravate rosacea. Many patients may also notice flares around the holidays, particularly Christmas and New Year's holidays.
Rosacea risk factors include fair skin, English, Irish, or Scottish heredity, easy blushing, and having other family members with rosacea (called "positive family history"). Additional risk factors include female gender, menopause, and being 30-50 years of age.
A man shows the common symptoms and signs of rosacea.

What are rosacea symptoms and signs?

Typical signs and symptoms of rosacea include
  • facial flushing,
  • blushing,
  • skin redness (erythema),
  • burning,
  • red bumps and pustules,
  • small cysts, and
  • thickening of the facial tissue, especially the nose.
The symptoms and signs of rosacea tend to come and go. The skin may be clear for weeks, months, or years and then erupt again. Rosacea tends to evolve in stages and typically causes inflammation of the skin of the face, particularly the forehead, cheeks, nose, and chin.
When rosacea first develops, it may appear, then disappear, and then reappear. However, the skin may fail to return to its normal color, and the enlarged blood vessels and pimples arrive in time. Rosacea rarely resolves spontaneously.
Rosacea generally lasts for years, and if untreated, it tends to gradually worsen.

How long does facial flushing from rosacea last?

Early in the course of rosacea, facial flushing is transient, lasting for minutes to hours. Later, as the disease progresses, the flushing becomes permanent and the redness does not resolve.

Is it possible to prevent rosacea?

It is not possible to prevent rosacea, but it is possible to limit one’s exposure to triggering factors. Once the diagnosis of rosacea is made, it is wise to avoid factors like spicy foods, hot liquids, smoking, and irritating cosmetics that are known to trigger rosacea.

A dermatologist examines a woman's skin under a light.

What tests do health care professionals use to diagnose rosacea?

Rosacea is usually diagnosed based on the typical red or blushed facial skin appearance and symptoms of easy facial blushing and flushing. Rosacea is largely underdiagnosed, and most people with rosacea do not know they have the skin condition. Many people may not associate their intermittent flushing symptoms with a medical condition. The facial redness in rosacea may be transient and come and go very quickly.
Dermatologists are physicians who are specially trained in the diagnosis of rosacea. Generally, no specific tests are required for the diagnosis of rosacea.
In unusual cases, a skin biopsy may be required to help confirm the diagnosis of rosacea. Occasionally, a noninvasive test called a skin scraping may be performed by the dermatologist in the office to help exclude a skin mite infestation by Demodex, which can look just like rosacea (and may be a triggering factor). A skin culture can help exclude other causes of facial skin bumps like staph infections or herpes infections. Blood tests are not generally required but may be used to help exclude less common causes of facial blushing and flushing, including systemic lupus, other autoimmune conditions, and dermatomyositis.
While most cases of rosacea are fairly straightforward, there are some atypical cases that are not as easy to diagnose. Other skin diseases and rosacea look-alikes include
Recently, there has been an association noted between rosacea and certain auto-inflammatory diseases, including diabetesinflammatory bowel disease, and cardiovascular disease.
A close-up of rosacea around the nose and eyes.

How does rosacea affect the nose and the eyes?

The nose is typically one of the first facial areas to be affected in rosacea. It can become red and bumpy and develop noticeable dilated small blood vessels. Left untreated, advanced stages of rosacea can cause a disfiguring nose condition called rhinophyma (ryno-fy-ma), literally growth of the nose, characterized by a bulbous, enlarged red nose and puffy cheeks (like the classic comedian W.C. Fields). There may also be thick bumps on the lower half of the nose and the nearby cheek areas. Rhinophyma occurs mainly in men. Severe rhinophyma can require surgical correction and repair.
Some people falsely attribute the prominent red nose to excessive alcohol intake, and this stigma can cause embarrassment to those with rosacea.
Rosacea may affect the eyes. Not everyone with rosacea has eye problems. A complication of advanced rosacea, known as ocular rosacea, affects the eyes. About half of all people with rosacea report feeling burning, dryness, and irritation of the tissue lining of the eyes (conjunctivitis). These individuals may also experience redness of the eyelids and light sensitivity. Often the eye symptoms may go completely unnoticed and not be a major concern for the individual. Many times, the physician or ophthalmologist may be the first one to notice the eye symptoms. Untreated, ocular rosacea may cause a serious complication that can damage the cornea permanently damaging vision, called rosacea keratitis. An ophthalmologist can assist in a proper eye evaluation and prescribe rosacea eyedrops. Oral antibiotics may be useful to treat skin and eye rosacea.

A man undergoes photodynamic light therapy for rosacea.

What about using acne medicine for rosacea?

Since there is some overlap between acne and rosacea, some of the medications may be similar. Acne and rosacea have in common several possible treatments, including (but not limited to) oral antibiotics, topical antibiotics, sulfa-based face washes, isotretinoin, and many others. It is important to seek a physician's advice before using random over-the-counteracne medications since they can actually irritate skin that is prone to rosacea. Overall, rosacea skin tends to be more sensitive and easily irritated than that of common acne.

Does rosacea get worse with age?

Yes. Although rosacea has a variable course and is not predictable in everyone, it tends to gradually worsen with age, especially if untreated. In small studies, many rosacea sufferers have reported that without treatment their condition had advanced from early to middle stage within a year. With good therapy, it is possible to prevent progression of rosacea.

What types of doctors treat rosacea?

Dermatologists are most familiar with which option might be best for each individual. Ophthalmologists treat rosacea-related eye disease.

From WebMD Logo

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