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· Does Osteoporosis Only Affect the Elderly?
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·
While the effects of osteoporosis are often seen in the elderly,
the disorder usually starts progressing from middle age on. Bones are their
strongest in a person's mid-twenties, so it is important to have a good
foundation early on to maintain healthy bones late in life.
Why Is Osteoporosis an Important Public
Health Issue?
In the United
States, 10 million people have osteoporosis (80% of those are women), and 34
million are at risk for developing the disease due to low bone density.
Osteoporosis is a public health issue because the disease contributes to 1.5
million fractures (broken bones), including 350,000 hip fractures annually.
The costs of medical care for these injures was an estimated $17 billion in
2005. These injuries can also result in permanent disability or an inability
to return to work or perform daily activities.
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What Are the Symptoms of Osteoporosis?
Osteoporosis may not cause any apparent symptoms. Patients may
not know they have osteoporosis until they break (fracture) a bonOsteoporosis Symptoms: Fractures of the Spine
Vertebral (spinal) compression fractures are broken bones in the
back that are due to weak bones caused by osteoporosis. The vertebrae (spinal
bone) collapses as a result of even minor injuries related to falling,
bending, twisting, or sneezing. As the bones of the spine lose their
mineralization and strength, they can collapse, causing a hunched-over
appearance, oOsteoporosis Symptoms: Stress Fracture
Stress
fractures occur in bones due to repetitive injuries, usually with minimal
trauma. Patients with osteoporosis are more prone to stress fractures because
of the weakness of their bones.
Osteoporosis Symptoms: Hip Fracture
Patients with
osteoporosis are at greater risk for hip fractures. Even a simple fall can
cause a hip fracture in a person with osteoporosis. Due to the weakness in
the bones these injuries may take a long time or be difficult to fully heal.
What Are the Consequences of Osteoporosis?
Fractures
related to osteoporosis can result in significant pain and disability. Hip
fractures are common among patients with osteoporosis. Twenty percent of hip
fracture patients die within one year following their injury, and one-third
will remain in a nursing home for at least a year.
Patients who
have one vertebral (spinal) compression fracture are at high risk for
developing other such fractures.
What Factors Determine
Bone Strength?
Bone strength is
related to bone mass (density), which refers to the amount of mineralization
remaining in bones as people age. The denser the bones, the stronger they
are.
Factors that determine
bone strength include:
·
Genetics
·
Environment
·
Medications
·
Ethnicity
(African-Americans have higher bone density than Caucasians or Asians)
·
Gender
(men have higher bone density than women)
·
Aging
(bone density reaches its peak around age 25, and decreases after age 35)
Menopause, Estrogen, and Osteoporosis
Women tend to
be diagnosed with osteoporosis more often than men because once they reach
menopause estrogen levels decrease. Estrogen helps maintain bone density in
women. Post-menopausal women can lose up to 4% of bone mass annually in the
first 10 years following menopause.
What Are the Risk
Factors for Developing Osteoporosis?
Risk factors for
developing osteoporosis that cannot be controlled include:
·
Female
gender
·
Ethnicity
– Caucasian or Asian
·
Family
history
Risk factors for
developing osteoporosis that can be controlled include:
·
Smoking
·
Lack
of exercise
·
Diets
lacking calcium
·
Poor
nutrition
·
Alcohol
abuse
What Are the Risk
Factors for Developing Osteoporosis? (continued)
Additional risk
factors for developing osteoporosis include medical conditions such as:
·
Chronically
low estrogen levels
·
Vitamin
D deficiency
·
Hyperthyroidism
·
Inability
to exercise
·
Medications,
such as chemotherapy, corticosteroids, or seizure medications
·
Hyperparathyroidism
How Is Osteoporosis Diagnosed?
Osteoporosis
is often diagnosed on an X-ray when the patient suffers a fracture. However,
by the time osteoporosis is visible on X-ray there may be significant bone
loss.
A dual energy
X-ray absorptiometry (DEXA or DXA) scan can be used as a screening test for
osteopenia (bone loss that precedes osteoporosis). This test measures bone
density in the hip and spine and is more precise than an X-ray.
Who Should Have Bone
Density Testing?
The National
Osteoporosis Foundation recommends the following groups of people should have
dual energy X-ray absorptiometry (DEXA or DXA) scans to screen for osteoporosis:
·
All
women age 65 and older
·
All
postmenopausal women under age 65 who have risk factors for osteoporosis
·
Postmenopausal
women with fractures
·
Women
with a medical condition associated with osteoporosis
How Are Bone Density
Results Measured?
The DXA scan lists
results as a "T score." This measurement is a statistical
comparison (SD, or standard deviation) of the patient's bone density compared
to the average peak bone density of a young adult of the same gender and
ethnicity.
·
A
T score of -1 to -2.5 SD is characteristic of osteopenia, which is a
precursor to osteoporosis
·
A
T score of -2.5 SD or below indicates osteoporosis
How Is Osteoporosis Treated and Prevented?
There is no
current cure for osteoporosis. Osteoporosis treatment involves stopping
further bone loss, and strengthening bones that show signs of weakness.
Prevention of osteoporosis is key.
Prevention and Treatment: Exercise
Exercise is
important in helping improve muscle strength and balance, which can decrease
falls and other accidents. Weight-bearing exercise also has the benefit of
helping to strengthen bones. Consult your doctor for the type and duration of
exercise that is right for you.
A Word of Caution About Exercise
In patients
with osteoporosis, exercise may injure weakened bones. It is important to
discuss with a health care practitioner the exercises that are appropriate
for patients with osteoporosis. It is also important to consider other
medical problems that may also be present (heart disease, diabetes, high
blood pressure) before starting any exercise program. Some types of extreme
exercise such as marathon running may not be recommended for patients with
osteoporosis.
Prevention and Treatment: Quit Smoking and
Curtail Alcohol
Smoking can
result in bone loss. In patients with osteoporosis this can accelerate the
progression of the disease. It also decreases estrogen levels in women, which
can lead to earlier menopause, and further bone loss.
Most
Americans do not get enough of the U.S. Recommended Daily Allowance (USRDA)
of calcium. Some examples of dietary sources of calcium include milk, yogurt,
cheese, and fortified orange juice.
. Prevention and Treatment: Vitamin D
In order to properly
absorb calcium in the diet and maintain good bone health, the body also needs
vitamin D for the following:
·
Absorption
of calcium from the intestines
·
Prevent
osteomalacia, which can further weaken bones
·
Increase
bone density and decrease fractures in postmenopausal women
The USRDA for vitamin
D is 600 IU (international units) per day for children age 1 year up to
adults of 70 years. Infants under 1 year need 400 IU, while adults 71 and
older require 800 IU.
Good sources of
vitamin D include sunlight, fatty fish such as salmon or mackerel, beef
liver, egg yolk, milk or orange juice fortified with vitamin D, fortified
cereals, and infant formulas.
Prevention and Treatment: Menopausal Hormone
Therapy
Because
estrogen can play a role in maintaining bone density and strength in women,
many menopausal women with osteoporosis are prescribed hormone therapy
(menopausal hormone therapy, formerly referred to as hormone replacement
therapy, or HRT) to prevent bone loss and fractures.
Estrogen may
be prescribed alone orally (Premarin, Estrace, Estratest) or as a skin patch
(Estraderm, Vivelle), or along with progesterone. The combination of the two
hormones can help prevent uterine cancer that can result from using estrogen
alone. Menopausal hormone therapy can have side effects including increased
risk of heart attack, stroke, blood clots, and breast cancer so it is not
typically recommended for long-term use. Consult a doctor for more
information on menopausal hormone replacement.
Prevention and Treatment: Medications
There are
several types of medications used to treat osteoporosis.
1.
Anti-resorptive drugs: These medications prevent bone resorption (breakdown)
and can help increase bone mass. Examples include alendronate (Fosamax),
risedronate (Actonel), raloxifene (Evista), ibandronate (Boniva), calcitonin
(Calcimar), and zoledronate (Reclast).
2. Menopausal
estrogen hormone therapy: this can act much as the anti-resorptive drugs do,
preventing bone loss and helping increase bone mass.
3. Selective
estrogen receptor modulators (SERMs): These medications work like estrogen,
and include tamoxifen and Raloxifene (Evista).
4. Anabolic
drugs: these are the only drugs that actually build bone mass. Teriparatide,
a form of parathyroid hormone, is one example of this type of drug
Prevention of Hip Fractures
Hip
protectors can reduce the risk of hip fractures in people who have
osteoporosis and are at risk for falls. Hip protectors are undergarments with
thin layers of foam or plastic on the hips. Hipsaver and Safehip are two of
the brands available.
Osteoporosis At A
Glance
·
Osteoporosis
is a disorder of the bones in which the bones become brittle, weak, and
easily damaged or broken.
·
Bone
mass (bone density) reaches its peak around age 25, and decreases after age
35 years and decreases more rapidly in women after menopause.
·
Risk
factors for osteoporosis include genetics, lack of exercise, lack of calcium
and vitamin D, cigarette smoking, excessive alcohol consumption, and family
history of osteoporosis.
·
Patients
with osteoporosis may have no symptoms until bone fractures occur.
·
Osteoporosis
may be diagnosed using X-rays but it is more likely to be detected with DEXA
scans which measure bone density.
·
Treatments
for osteoporosis include prescription osteoporosis medications, quitting
smoking, and getting appropriate exercise, calcium, and vitamin D.
Prevention of Hip Fractures
Hip
protectors can reduce the risk of hip fractures in people who have
osteoporosis and are at risk for falls. Hip protectors are undergarments with
thin layers of foam or plastic on the hips. Hipsaver and Safehip are two of
the brands available.
Reviewed by Aimee V. HachigianGould, MD on Wednesday, July 27, 2016
What Is Osteoporosis?
Treatment, Symptoms, Medication
This tool does
not provide medical advice.
e.
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