Get a Grip on Rheumatoid Arthritis ( courtecy;- medicine.com ) Rheumatoid arthritis is a disease where the body attacks the lining .tissue of joints
Get a Grip on Rheumatoid Arthritis ( courtecy;- medicine.com )
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Rheumatoid arthritis is a disease where the body attacks the
lining tissue of joints.
Are Your Bones
at Risk for Osteoporosis?
What Is
Osteoporosis?
Osteoporosis is
a disorder of the bones in which the bones become brittle, weak, and easily
damaged or broken. A decrease in the mineralization and strength of the bones
over time causes osteoporosis.
Does
Osteoporosis Only Affect the Elderly?
While the effects
of osteoporosis are often seen in the elderly, the disorder usually starts
progressing from middle age on. Bones are their strongest in a person's
mid-twenties, so it is important to have a good foundation early on to maintain
healthy bones late in life.
Why Is
Osteoporosis an Important Public Health Issue?
In the United
States, 10 million people have osteoporosis (80% of those are women), and 34
million are at risk for developing the disease due to low bone density.
Osteoporosis is a public health issue because the disease contributes to 1.5
million fractures (broken bones), including 350,000 hip fractures annually. The
costs of medical care for these injures was an estimated $17 billion in 2005.
These injuries can also result in permanent disability or an inability to
return to work or perform daily activities.
What Are the
Symptoms of Osteoporosis?
Osteoporosis
may not cause any apparent symptoms. Patients may not know they have osteoporosis
until they break (fracture) a bone.
Osteoporosis
Symptoms: Fractures of the Spine
Vertebral
(spinal) compression fractures are broken bones in the back that are due to
weak bones caused by osteoporosis. The vertebrae (spinal bone) collapses as a
result of even minor injuries related to falling, bending, twisting, or
sneezing. As the bones of the spine lose their mineralization and strength,
they can collapse, causing a hunched-over appearance, often referred to as a
"dowager hump."
Osteoporosis
Symptoms: Stress Fracture
Stress
fractures occur in bones due to repetitive injuries, usually with minimal
trauma. Patients with osteoporosis are more prone to stress fractures because
of the weakness of their bones.
Osteoporosis
Symptoms: Hip Fracture
Patients with
osteoporosis are at greater risk for hip fractures. Even a simple fall can
cause a hip fracture in a person with osteoporosis. Due to the weakness in the
bones these injuries may take a long time or be difficult to fully heal.
What Are the
Consequences of Osteoporosis?
Fractures
related to osteoporosis can result in significant pain and disability. Hip
fractures are common among patients with osteoporosis. Twenty percent of hip
fracture patients die within one year following their injury, and one-third
will remain in a nursing home for at least a year.
Patients who
have one vertebral (spinal) compression fracture are at high risk for
developing other such fractures.
What Factors
Determine Bone Strength?
Bone strength
is related to bone mass (density), which refers to the amount of mineralization
remaining in bones as people age. The denser the bones, the stronger they are.
Factors that
determine bone strength include:
·
Genetics
·
Environment
·
Medications
·
Ethnicity (African-Americans have higher bone density than
Caucasians or Asians)
·
Gender (men have higher bone density than women)
·
Aging (bone density reaches its peak around age 25, and decreases
after age 35)
Menopause,
Estrogen, and Osteoporosis
Women tend to
be diagnosed with osteoporosis more often than men because once they reach
menopause estrogen levels decrease. Estrogen helps maintain bone density in
women. Post-menopausal women can lose up to 4% of bone mass annually in the
first 10 years following menopause.
Menopause,
Estrogen, and Osteoporosis
Women tend to
be diagnosed with osteoporosis more often than men because once they reach
menopause estrogen levels decrease. Estrogen helps maintain bone density in
women. Post-menopausal women can lose up to 4% of bone mass annually in the
first 10 years following menopause.
What Are the
Risk Factors for Developing Osteoporosis?
Risk factors
for developing osteoporosis that cannot be controlled include:
·
Female gender
·
Ethnicity – Caucasian or Asian
·
Family history
Risk factors
for developing osteoporosis that can be controlled include:
·
Smoking
·
Lack of exercise
·
Diets lacking calcium
·
Poor nutrition
·
Alcohol abuse
What Are the
Risk Factors for Developing Osteoporosis? (continued)
Additional risk
factors for developing osteoporosis include medical conditions such as:
·
Chronically low estrogen levels
·
Vitamin D deficiency
·
Hyperthyroidism
·
Inability to exercise
·
Medications, such as chemotherapy, corticosteroids, or seizure
medications
·
Hyperparathyroidism
How Is
Osteoporosis Diagnosed?
Osteoporosis is
often diagnosed on an X-ray when the patient suffers a fracture. However, by
the time osteoporosis is visible on X-ray there may be significant bone loss.
A dual energy
X-ray absorptiometry (DEXA or DXA) scan can be used as a screening test for
osteopenia (bone loss that precedes osteoporosis). This test measures bone
density in the hip and spine and is more precise than an X-ray.
How Is
Osteoporosis Diagnosed?
Osteoporosis is
often diagnosed on an X-ray when the patient suffers a fracture. However, by
the time osteoporosis is visible on X-ray there may be significant bone loss.
A dual energy
X-ray absorptiometry (DEXA or DXA) scan can be used as a screening test for
osteopenia (bone loss that precedes osteoporosis). This test measures bone
density in the hip and spine and is more precise than an X-ray.
How Is
Osteoporosis Diagnosed?
Osteoporosis is
often diagnosed on an X-ray when the patient suffers a fracture. However, by
the time osteoporosis is visible on X-ray there may be significant bone loss.
A dual energy
X-ray absorptiometry (DEXA or DXA) scan can be used as a screening test for
osteopenia (bone loss that precedes osteoporosis). This test measures bone
density in the hip and spine and is more precise than an X-ray.
Who Should
Have Bone Density Testing?
The National
Osteoporosis Foundation recommends the following groups of people should have
dual energy X-ray absorptiometry (DEXA or DXA) scans to screen for
osteoporosis:
·
All women age 65 and older
·
All postmenopausal women under age 65 who have risk factors for
osteoporosis
·
Postmenopausal women with fractures
·
Women with a medical condition associated with osteoporosis
How Are Bone
Density Results Measured?
The DXA scan
lists results as a "T score." This measurement is a statistical
comparison (SD, or standard deviation) of the patient's bone density compared
to the average peak bone density of a young adult of the same gender and
ethnicity.
·
A T score of -1 to -2.5 SD is characteristic of osteopenia, which
is a precursor to osteoporosis
·
A T score of -2.5 SD or below indicates osteoporosis
How Is
Osteoporosis Treated and Prevented?
There is no
current cure for osteoporosis. Osteoporosis treatment involves stopping further
bone loss, and strengthening bones that show signs of weakness. Prevention of osteoporosis
is key.
Prevention and
Treatment: Exercise
Exercise is
important in helping improve muscle strength and balance, which can decrease
falls and other accidents. Weight-bearing exercise also has the benefit of
helping to strengthen bones. Consult your doctor for the type and duration of
exercise that is right for you.
A Word of
Caution About Exercise
In patients
with osteoporosis, exercise may injure weakened bones. It is important to
discuss with a health care practitioner the exercises that are appropriate for
patients with osteoporosis. It is also important to consider other medical
problems that may also be present (heart disease, diabetes, high blood
pressure) before starting any exercise program. Some types of extreme exercise
such as marathon running may not be recommended for patients with osteoporosis.
Prevention and
Treatment: Quit Smoking and Curtail Alcohol
Smoking can
result in bone loss. In patients with osteoporosis this can accelerate the
progression of the disease. It also decreases estrogen levels in women, which
can lead to earlier menopause, and further bone loss.
The effect of
alcohol and caffeine on osteoporosis is not clear. To maintain optimal heath,
consume alcohol and caffeine in moderation.
Prevention and
Treatment: Calcium Supplements
Calcium intake
is important for strong and healthy bones. Adequate calcium intake must occur
earlier in life to help prevent osteopenia and osteoporosis.
Recommended
calcium intake for all adults and female teens is 1,000-1,300 mg daily. Good
sources of dietary calcium include dairy products, vegetables (kale, cabbage,
broccoli, spinach), and fortified foods (fruit juices, non-dairy milks,
cereals). Postmenopausal women may need more calcium.
Prevention and
Treatment: Calcium-Fortified Foods
Most Americans
do not get enough of the U.S. Recommended Daily Allowance (USRDA) of calcium.
Some examples of dietary sources of calcium include milk, yogurt, cheese, and
fortified orange juice.
Prevention and
Treatment: Vitamin D
In order to
properly absorb calcium in the diet and maintain good bone health, the body
also needs vitamin D for the following:
·
Absorption of calcium from the intestines
·
Prevent osteomalacia, which can further weaken bones
·
Increase bone density and decrease fractures in postmenopausal
women
The USRDA for
vitamin D is 600 IU (international units) per day for children age 1 year up to
adults of 70 years. Infants under 1 year need 400 IU, while adults 71 and older
require 800 IU.
Good sources of
vitamin D include sunlight, fatty fish such as salmon or mackerel, beef liver,
egg yolk, milk or orange juice fortified with vitamin D, fortified cereals, and
infant formulas.
Prevention and
Treatment: Vitamin D
In order to
properly absorb calcium in the diet and maintain good bone health, the body
also needs vitamin D for the following:
·
Absorption of calcium from the intestines
·
Prevent osteomalacia, which can further weaken bones
·
Increase bone density and decrease fractures in postmenopausal
women
The USRDA for
vitamin D is 600 IU (international units) per day for children age 1 year up to
adults of 70 years. Infants under 1 year need 400 IU, while adults 71 and older
require 800 IU.
Good sources of
vitamin D include sunlight, fatty fish such as salmon or mackerel, beef liver,
egg yolk, milk or orange juice fortified with vitamin D, fortified cereals, and
infant formulas.
Prevention and
Treatment: Menopausal Hormone Therapy
Because
estrogen can play a role in maintaining bone density and strength in women,
many menopausal women with osteoporosis are prescribed hormone therapy
(menopausal hormone therapy, formerly referred to as hormone replacement
therapy, or HRT) to prevent bone loss and fractures.
Estrogen may be
prescribed alone orally (Premarin, Estrace, Estratest) or as a skin patch
(Estraderm, Vivelle), or along with progesterone. The combination of the two
hormones can help prevent uterine cancer that can result from using estrogen
alone. Menopausal hormone therapy can have side effects including increased
risk of heart attack, stroke,
Prevention and
Treatment: Medications
There are
several types of medications used to treat osteoporosis.
1. Anti-resorptive
drugs: These medications prevent bone resorption (breakdown) and can help
increase bone mass. Examples include alendronate (Fosamax), risedronate
(Actonel), raloxifene (Evista), ibandronate (Boniva), calcitonin (Calcimar),
and zoledronate (Reclast).
2. Menopausal
estrogen hormone therapy: this can act much as the anti-resorptive drugs do,
preventing bone loss and helping increase bone mass.
3. Selective
estrogen receptor modulators (SERMs): These medications work like estrogen, and
include tamoxifen and Raloxifene (Evista).
4. Anabolic
drugs: these are the only drugs that actually build bone mass. Teriparatide, a
form of parathyroid hormone, is one example of this type of drug
Prevention of
Hip Fractures
Hip protectors
can reduce the risk of hip fractures in people who have osteoporosis and are at
risk for falls. Hip protectors are undergarments with thin layers of foam or
plastic on the hips. Hipsaver and Safehip are two of the brands available.
Osteoporosis
At A Glance
·
Osteoporosis is a disorder of the bones in which the bones become
brittle, weak, and easily damaged or broken.
·
Bone mass (bone density) reaches its peak around age 25, and
decreases after age 35 years and decreases more rapidly in women after
menopause.
·
Risk factors for osteoporosis include genetics, lack of exercise,
lack of calcium and vitamin D, cigarette smoking, excessive alcohol
consumption, and family history of osteoporosis.
·
Patients with osteoporosis may have no symptoms until bone
fractures occur.
·
Osteoporosis may be diagnosed using X-rays but it is more likely
to be detected with DEXA scans which measure bone density.
·
Treatments for osteoporosis include prescription osteoporosis
medications, quitting smoking, and getting appropriate exercise, calcium, and
vitamin D.
·
Reviewed by Aimee V. HachigianGould, MD on Wednesday, July 27, 2016
·
What Is
Osteoporosis? Treatment, Symptoms, Medication
·
·
Sources:
·
This tool does not
provide medical advice
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