This New Treatment Makes Cancer Cells “Self Destruct,” Scientists Say This research is really promising. (Source: HuffPost UK] ) courtecy;- Reader’s Digest ) BY BROOKE NELSON
This New
Treatment Makes Cancer Cells “Self Destruct,” Scientists Say
This
research is really promising. (Source: HuffPost UK] ) courtecy;- Reader’s
Digest )
BY BROOKE
NELSON
Good news:
The future of cancer treatment has arrived. And among all of the recent genius
cancer breakthroughs, this one certainly takes the cake. Scientists have just
revealed a compound that makes cancer cells “self-destruct”—without harming
healthy cells.
According to
the research team at Albert Einstein College of Medicine, which discovered the
compound, the treatment can activate apoptosis, a process in the human body
that removes unwanted or faulty cells. (On the flip side, this one common food
could make cancer cells multiply.)
During
apoptosis, the “executioner protein” located within a cell—called BAX—targets
and dismantles its energy-producing mechanisms, causing the cell to “commit
suicide.” Unfortunately, cancer cells can suppress BAX, which allows them to
spread.
Knowing
this, senior author Dr. Gavathiotis and his team aimed to find a compound that
could strengthen the ability of BAX against cancer cells. They used computers
to screen over a million different compounds, eventually narrowing their search
down to just one: a compound called BTSA1 (short for BAX Trigger Site Activator
1).
When the
researchers tested BTSA1 on human blood samples from patients with a high risk
of acute myeloid leukemia, they found that the BTSA1 caused the AML cells to
self-destruct while leaving the healthy cells unharmed. What’s more, mice
treated with BTSA1 had a longer survival rate, and 43 percent survived longer
than 60 days and no longer carried AML in their system.
“Our novel
compound revives suppressed BAX molecules in cancer cells by binding with high
affinity to BAX’s activation site,” Dr. Gavathiotis told HuffPost UK. “BAX can
then swing into action, killing cancer cells while leaving healthy cells unscathed.”
Scientists
hope that future research will determine if BTSA1 is effective on other types
of cancers, as well. Until then, those worried about their risk can memorize
these 30 simple ways to prevent cancer.
[Source:
HuffPost UK]
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